{"id":"n_3of5kzkeok4t5xm3ak6q","seq":10822028,"kind":"article","title":"Mapping an enzyme offers clues to treating rare genetic disease","url":"https://medicalxpress.com/news/2026-11-enzyme-clues-rare-genetic-disease.html","summary":"Researchers at the Icahn School of Medicine at Mount Sinai have mapped an enzyme that could be targeted to develop new treatments for glutaric aciduria type 1 (GA1), a rare genetic disorder that can lead to brain damage, revealing new details about how the enzyme works and how its activity is controlled. The findings were published in Science Advances.","published":"2026-11-13T19:00:20Z","seen":"2026-11-13T19:01:54Z","lang":"en","country":"IM","source":{"id":"kite-medicalxpress-com-b50135","name":"medicalxpress.com","domain":"medicalxpress.com"},"via":"kite-medicalxpress-com-b50135","topics":["medicine"],"image":"https://scx1.b-cdn.net/csz/news/tmb/2026/mapping-an-enzyme-offe.jpg","story":"st_3of5kzkeok4t5xm3ak6q","category":"health","category_p":0.53,"category2":"science-technology","sentiment":"neutral","tone":0.28,"political":0.01}