{"schema":"hottub-news/list/v1","item_schema":"hottub-news/item/v1","count":2,"sponsored":0,"items":[{"id":"n_zeocoptiqmvsi7kbx72q","seq":1431947,"kind":"article","title":"Jaypirca approval expanded to include treatment-naive CLL, small lymphocytic lymphoma","url":"https://www.healio.com/news/hematology-oncology/20261002/jaypirca-approval-expanded-to-include-treatmentnaive-cll-small-lymphocytic-lymphoma","summary":"The FDA expanded the approval of pirtobrutinib to include initial treatment of adults with chronic lymphocytic leukemia or small lymphocytic lymphoma with no known 17p deletion. Pirtobrutinib (Jaypirca, Eli Lilly & Co.) — a selective, noncovalent Bruton’s tyrosine kinase (BTK) inhibitor — already had been approved for patients with relapsed or refractory CLL or small lymphocytic lymphoma (SLL) who already received a BTK inhibitor. It also is approved for certain patients…","published":"2026-10-02T20:59:07Z","seen":"2026-10-02T21:20:29Z","lang":"en","source":{"id":"kite-healio-com-23151b","name":"healio.com","domain":"healio.com"},"via":"kite-healio-com-23151b","topics":["medicine"],"authors":["Mark Leiser"],"entities":[{"id":"Q116622551","name":"pirtobrutinib","type":"other"},{"id":"Q1088156","name":"chronic lymphocytic leukemia","type":"other"}],"mentions":2,"story":"st_zeocoptiqmvsi7kbx72q","category":"health","category_p":0.71,"sentiment":"neutral","tone":0.32,"political":0.1},{"id":"n_hf3mdogwmaxv4iik4weq","seq":1428770,"kind":"article","title":"FDA Approves Jaypirca as First-Line Treatment for CLL and SLL","url":"https://www.curetoday.com/view/fda-approves-jaypirca-as-first-line-treatment-for-cll-and-sll","published":"2026-10-02T19:51:00Z","seen":"2026-10-02T21:09:44Z","lang":"en","source":{"id":"curetoday.com","name":"curetoday.com","domain":"curetoday.com","outlet":{"wikidata":"Q5014714","name":"CURE","type":"magazine","designations":["magazine","website"]}},"via":"gdelt-gkg-english","topics":["education","economy","health"],"entities":[{"id":"Q204711","name":"United States Food and Drug Administration","type":"org"},{"id":"Q116622551","name":"pirtobrutinib","type":"other"},{"id":"Q1088156","name":"chronic lymphocytic leukemia","type":"other"},{"id":"Q107969614","name":"SLL","type":"other"}],"story":"st_hf3mdogwmaxv4iik4weq","category":"health","category_p":0.8,"sentiment":"positive","tone":-0.34,"political":0.12}]}