{"schema":"hottub-news/list/v1","item_schema":"hottub-news/item/v1","count":5,"sponsored":0,"items":[{"id":"n_ccd3td3vj2jspe7z7dgq","seq":793431,"kind":"article","title":"'타그리소' 약효 떨어진 폐암에…AZ·허치메드, 병용치료 美 허가신청","title_en":"'Tagrisso' effectiveness declines in lung cancer... AZ and Hutchmed apply for combination therapy approval in the US","url":"https://www.medipana.com/news/articleView.html?idxno=418445","summary":"아스트라제네카와 허치메드가 \\'타그리소\\' 치료 후 진행한 폐암에 두 경구 표적치료제를 병용하는 전략으로 미국 허가에 도전한다. 기존 EGFR 표적치료에 내성이 생긴 환자 가운데 MET 이상이 확인된 환자를 겨냥한 치료법이다. 허치메드는 29일 아스트라제네카(AstraZeneca, AZ)가 \\'오파티스\\'(ORPATHYS·성분명 사볼리티닙)와 \\'타그리소\\'(오시머티닙) 병용요법의 신약허가신청서(NDA)를 미국 식품의약국(FDA)에 제출했다고 밝혔다. 신청 대상은 EGFR 티로신키나아제 억제제(TKI) 치료 중 또는 치료 후 질병이 진행하고,","published":"2026-09-29T22:40:46Z","seen":"2026-09-30T00:15:49Z","lang":"ko","source":{"id":"kite-cdn-medipana-com-912f9c","name":"cdn.medipana.com","domain":"cdn.medipana.com"},"via":"kite-cdn-medipana-com-912f9c","topics":["medicine","파마시안"],"authors":["최봉선 기자"],"entities":[{"id":"Q731938","name":"AstraZeneca","type":"org"},{"id":"Q113510355","name":"Hutchison MediPharma 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Administration","type":"org"}],"story":"st_3fql2tu6i4ezck7fz7ya","category":"health","category_p":0.57,"sentiment":"neutral","tone":-0.07,"political":0.34},{"id":"n_lytvs5izwl535uuk3o5a","seq":570244,"kind":"article","title":"AstraZeneca files US FDA application for HUTCHMED lung cancer drug combination","url":"https://www.thehindubusinessline.com/companies/astrazeneca-files-us-fda-application-for-hutchmed-lung-cancer-drug-combination/article71522392.ece","summary":"The treatment targets patients whose ⁠cancer progressed following prior EGFR-targeted treatment","published":"2026-09-29T03:14:17Z","seen":"2026-09-29T03:37:25Z","lang":"en","country":"IN","source":{"id":"kite-thehindubusinessline-com-b0e07f","name":"thehindubusinessline.com","domain":"thehindubusinessline.com","outlet":{"wikidata":"Q279739","name":"Business 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Cancer","url":"https://www.manilatimes.net/2026/09/29/tmt-newswire/globenewswire/hutchmed-announces-submission-of-us-nda-for-orpathys-plus-tagrisso-in-met-driven-egfr-mutated-lung-cancer/2434594","published":"2026-09-29T00:03:00Z","seen":"2026-09-29T01:37:58Z","lang":"en","source":{"id":"manilatimes.net","name":"manilatimes.net","domain":"manilatimes.net","outlet":{"wikidata":"Q1573100","name":"The Manila Times","type":"magazine","country":"PH","designations":["organization","periodical"]}},"via":"gdelt-gkg-english","topics":["economy","politics","business","health"],"entities":[{"id":"Q113510355","name":"Hutchison MediPharma Limited","type":"org"},{"id":"Q29006526","name":"Tagrisso","type":"other"}],"story":"st_3fql2tu6i4ezck7fz7ya","category":"health","category_p":0.63,"sentiment":"neutral","tone":-0.02,"political":0.16},{"id":"n_gqcu56obzf3ufwjhxioa","seq":330821,"kind":"article","title":"HUTCHMED Initiates Global Trial of KRAS-EGFR-Antibody Conjugate Therapy HMPL-A830 in Patients with Solid Tumors","url":"https://www.manilatimes.net/2026/09/28/tmt-newswire/globenewswire/hutchmed-initiates-global-trial-of-kras-egfr-antibody-conjugate-therapy-hmpl-a830-in-patients-with-solid-tumors/2433738","published":"2026-09-28T00:03:00Z","seen":"2026-09-28T03:07:15Z","lang":"en","source":{"id":"manilatimes.net","name":"manilatimes.net","domain":"manilatimes.net","outlet":{"wikidata":"Q1573100","name":"The Manila Times","type":"magazine","country":"PH","designations":["organization","periodical"]}},"via":"gdelt-gkg-english","topics":["economy","health","business"],"entities":[{"id":"Q113510355","name":"Hutchison MediPharma Limited","type":"org"}],"story":"st_aoggqabsokz5lwkm5xfa","category":"health","category_p":0.68,"sentiment":"neutral","tone":-0.01,"political":0.08}]}