{"schema":"hottub-news/story/v1","story":"st_ezifsbyxycraere2ul4a","title":"台大研究揭大腸癌免疫治療抗藥關鍵 TXNDC5成突破口","title_en":"NTU research reveals key to colorectal cancer immunotherapy resistance: TXNDC5 becomes breakthrough","outlets":1,"brief":null,"page":"https://hottub.news/stories/ntu-research-reveals-key-to-colorectal-cancer-immunotherapy-resistance-ezifsbyxyc","count":1,"items":[{"id":"n_ezifsbyxycraere2ul4a","seq":1464526,"kind":"article","title":"台大研究揭大腸癌免疫治療抗藥關鍵 TXNDC5成突破口","title_en":"NTU research reveals key to colorectal cancer immunotherapy resistance: TXNDC5 becomes breakthrough","url":"https://health.ltn.com.tw/article/breakingnews/5593947","summary":"大腸直腸癌接受免疫治療，為何有些腫瘤就是難以攻破？國立台灣大學醫學院藥理學研究所教授楊鎧鍵研究團隊找到關鍵機制，發現內質網蛋白「TXNDC5」會促使癌症相關成纖維細胞持續...…","published":"2026-10-03T01:52:36Z","seen":"2026-10-03T02:29:12Z","lang":"zh","country":"TW","source":{"id":"kite-news-ltn-com-tw-3ff025","name":"news.ltn.com.tw","domain":"news.ltn.com.tw"},"via":"kite-news-ltn-com-tw-3ff025","entities":[{"id":"Q32746","name":"National Taiwan University","type":"org"}],"story":"st_ezifsbyxycraere2ul4a","category":"health","category_p":0.6899999976158142,"sentiment":"positive","tone":0.4699999988079071,"political":0.05999999865889549}]}