{"schema":"hottub-news/story/v1","story":"st_nh7zjeoy5gh4rbbe6m2a","title":"Wave Life Sciences Announces FDA Feedback Supports Registrational Pathway for WVE-006 (RNA Editing) in AATD","title_en":null,"outlets":2,"brief":null,"page":"https://hottub.news/stories/wave-life-sciences-announces-fda-feedback-supports-registrational-nh7zjeoy5g","count":2,"items":[{"id":"n_e7g5lj4kdg4cvhs7mevq","seq":1135078,"kind":"article","title":"Wave Life Sciences Announces FDA Feedback Supports Registrational Pathway for WVE-006 (RNA Editing) in AATD","url":"https://www.manilatimes.net/2026/10/01/tmt-newswire/globenewswire/wave-life-sciences-announces-fda-feedback-supports-registrational-pathway-for-wve-006-rna-editing-in-aatd/2437002","published":"2026-10-01T11:40:00Z","seen":"2026-10-01T12:23:53Z","lang":"en","source":{"id":"manilatimes.net","name":"manilatimes.net","domain":"manilatimes.net","outlet":{"wikidata":"Q1573100","name":"The Manila Times","type":"magazine","country":"PH","designations":["organization","periodical"]}},"via":"gdelt-gkg-english","topics":["economy","health","business","science"],"entities":[{"id":"Q91396922","name":"Wave Life Sciences","type":"org"},{"id":"Q204711","name":"United States Food and Drug Administration","type":"org"},{"id":"Q622437","name":"alpha-1-antitrypsin deficiency","type":"other"}],"story":"st_nh7zjeoy5gh4rbbe6m2a","category":"science-technology","category_p":0.75,"sentiment":"neutral","tone":0.10000000149011612,"political":0.029999999329447746},{"id":"n_nh7zjeoy5gh4rbbe6m2a","seq":1124391,"kind":"press_release","title":"Wave Life Sciences Announces FDA Feedback Supports Registrational Pathway for WVE-006 (RNA Editing) in AATD","url":"https://www.globenewswire.com/news-release/2026/10/01/3372774/0/en/wave-life-sciences-announces-fda-feedback-supports-registrational-pathway-for-wve-006-rna-editing-in-aatd.html","summary":"Following meeting with FDA, Wave plans for a single, two-year registrational trial, with a one-year interim analysis for potential accelerated approval based on AATD biomarkers","published":"2026-10-01T11:30:00Z","seen":"2026-10-01T11:35:31Z","lang":"en","source":{"id":"globenewswire-public","name":"GlobeNewswire — public companies","domain":"globenewswire.com","outlet":{"wikidata":"Q5570956","name":"GlobeNewswire","type":"other","country":"US","designations":["business","press release distributor"]}},"via":"globenewswire-public","topics":["business","nasdaq:wve","sg9999014716"],"entities":[{"id":"Q91396922","name":"Wave Life Sciences","type":"org"}],"story":"st_nh7zjeoy5gh4rbbe6m2a","category":"science-technology","category_p":0.75,"sentiment":"neutral","tone":0.41999998688697815,"political":0.029999999329447746}]}